Director, Marketing – MPS I and ASMD

Job title: Director, Marketing – MPS I and ASMD

• Location: Cambridge, MA

About the Job

The Director, Marketing – MPS I and ASMD is the brand strategy lead for Sanofi's ASMD and MPS I disease portfolio, encompassing Xenpozyme® (olipudase alfa) for Acid Sphingomyelinase Deficiency (ASMD) and Aldurazyme® (laronidase) for Mucopolysaccharidosis I (MPS I). This role owns brand strategy, campaign and messaging platform, brand planning process, and core team governance for these two disease areas, and serves as the primary U.S.-to-Global commercial partner for both brands.

The Director directly manages and develops a team of three — a Patient Experience Marketer, an HCP Experience Marketer, and a PharmD Fellow bringing strong people leadership, strategic thinking, and rare disease commercial expertise to the role.

A defining priority of this position is leading the transition of both the ASMD and MPS I brand away from traditional agency-dependent models toward a fully AI/digital marketing platform. This includes building internal digital capabilities, owning content and campaign production digitally, and systematically reducing reliance on external creative and media agencies over time — positioning this portfolio as a model for digital-first, agile brand marketing within Sanofi Rare Disease.

Join the team transforming care for people with immune challenges, rare diseases, cancers, and Specialty Care neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs.

About Sanofi

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives. 

Main Responsibilities

Brand Strategy – ASMD & MPS I Portfolio

• Own the U.S. brand strategy for Xenpozyme and Aldurazyme, ensuring each brand maintains compelling, differentiated, and commercially sound strategic positioning

• Develop and maintain the strategic framework for the ASMD and MPS I portfolio, including portfolio prioritization, lifecycle management, and competitive response strategies

• Ensure brand strategies are grounded in data, customer insights, competitive intelligence, and clinical data, addressing the full patient journey

• Anticipate market dynamics and proactively evolve brand positioning to reflect the evolving ASMD and MPS I treatment landscapes

Digital-First Brand Campaign & Messaging

• Own the brand campaign and messaging platform for ASMD and MPS I, ensuring compelling, differentiated, and compliant brand narratives for both HCP and patient audiences

• Lead the development and evolution core messaging, visual identity, and campaign architecture for Xenpozyme and Aldurazyme

• Drive the transition to a no-agency, fully in-house digital marketing model, building internal digital production capabilities, establishing in-house content creation workflows, and architecting a digital-first campaign infrastructure

• Ensure campaign and messaging alignment across all digital channels and tactics, leveraging internal teams to execute with speed and precision

• Champion a culture of digital innovation, testing, and optimization across the ASMD and MPS I brand teams

Brand Plan Leadership

• Lead the annual brand planning process for the ASMD and MPS I portfolio, including situation analysis, strategic imperatives, tactical planning, and resource allocation

• Integrate digital transformation milestones and in-house capability-building objectives into annual brand plans

• Present brand plans to senior leadership, including the Head Rare/xLSD Marketing and cross-functional leadership, with clear strategic rationale and measurable outcomes

• Ensure brand plans reflect the needs of rare disease patients and caregivers, consistent with Sanofi's mission-driven approach to rare diseases

Team Leadership & Development

• Directly manage and develop a team of three direct reports: Patient Experience Marketer, HCP Experience Marketer, and PharmD Fellow

• Set individual goals aligned to brand priorities and the digital transformation agenda; provide ongoing coaching, feedback, and career development support

• Foster a team culture grounded in digital innovation, agility, patient-centricity, and continuous learning

• Serve as a visible and accessible people leader who models Sanofi's values and commitment to rare disease patients

Core Team Governance

• Lead core team governance for the ASMD and MPS I brands, chairing or co-chairing core team meetings and ensuring cross-functional alignment on brand strategy and execution

• Drive accountability for brand plan execution across the core team, tracking milestones and escalating issues as needed

• Ensure governance processes support the pace and agility required by the in-house digital marketing model

Forecasting & KPI Development

• Serve as the commercial forecasting and KPI development partner for the ASMD and MPS I portfolio, working closely with Finance, GTMC, and the Head Rare/xLSD Marketing

• Develop and track brand KPIs, including digital engagement and performance metrics as the marketing platform transitions in-house

• Monitor performance against forecast and provide regular, data-driven updates to leadership

• Use KPI insights to inform brand strategy adjustments and optimize resource allocation

Global Partnership

• Serve as the primary U.S. commercial partner to the Global ASMD and MPS I brand teams, ensuring alignment between U.S. execution and global brand strategy

• Represent the U.S. commercial perspective in global brand forums and contribute to global brand planning processes

• Ensure that U.S. digital-first and in-house marketing innovations are shared with and inform global brand thinking where appropriate

About You

• Bachelor's degree required; MBA or advanced degree strongly preferred

• Demonstrated ability to lead, coach, and develop direct reports in a fast-paced, complex environment

• Experience managing multiple brands or indications simultaneously preferred

• Strong track record of leading brand planning processes and developing brand campaign strategies

• Strong analytics

• Proven ability to partner effectively with Global brand teams across geographies and functions

• Excellent cross-functional collaboration, communication, and executive presentation skills

Why Choose Us

• Bring the miracles of science to life alongside a supportive, future-focused team. 

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. 

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. 

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. 

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.