Senior Analytical Chemist - Solid State Characterization

Job title: Senior Analytical Chemist - Solid State Characterization

• Location: Cambridge, MA

About the job

Sanofi is seeking a highly motivated individual to join our analytical group as a Senior Scientist for Solid State Characterization. The group is part of the synthetic platform within Global CMC Development that is striving to become an industry leader in the development of transformative medicines.

The primary responsibility of this solid-state characterization expert position is to lead/implement polymorphism/salt studies and act as the solid-state representative on development projects.

Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

About Sanofi:

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world and are supported and enhanced through our diverse portfolio of medical device and diagnostic products. Together, we chase the miracles of science to improve people’s lives.

Main Responsibilities:

• Lead and perform polymorphism studies for synthetics molecules, including polymorph screening, in depth physical characterization and thermodynamic assessment

• Design and conduct salt selection studies (salt screening, in depth physical characterization and stability assessment, …)

• Act as the solid-state representative on development projects to deploy solid-form selection strategy in collaboration with other functions (e.g., Crystallization, Biopharm and Chemistry)

• Develop and implement analytical methods using equipment including XRPD, DSC, TGA, SEM, Raman, IR, and laser granulometry

• Provide physical characterization support (e.g, XRPD, PDS, etc) to internal partner teams

• Use computational tools to perform Crystal Structure Prediction studies

• Generate technical reports independently

• Develop effective collaborations with others within project teams and between analytical groups

• Introduce innovative analytical approaches to facilitate optimal decision-making, including automation and AI/modeling integration

• Promote scientific excellence through internal and external presentations and publications

About you

Education:

• PhD in chemistry, pharmaceutical science, material science, or related fields with minimum 3 years of postdoctoral experience in a pharma or biopharma environment

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Experience & Technical Skills:

• In-depth experience with solid-state characterization instruments: XRPD, DSC, TGA

• Expertise in polymorphism/salt selection and understanding of powder and particle properties

• In-depth understanding of pharmaceutical solid-state properties

Preferred Qualifications:

• Experience with SEM, Raman, IR, or laser granulometry

• Demonstrated expertise in crystallography and computational prediction

• Experience in crystal structure resolution by sc-XRD

• Experience in crystallization of synthetic molecules (e.g., crystallization process, single-crystal growth, etc.)

• Having an established scientific network in the industry and academia

Soft Skills:

• Good oral and written communication skills and ability to communicate effectively in individual and group settings

• Ability to collaborate effectively in a multi-disciplinary team environment

• Record of adhering to and promoting lab safety practices

• Open-minded, agile, and capable of innovating in a complex environment

Why choose us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.

• Help improve the lives of millions of people globally by making drug development quicker and more effective.

• Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.