Vaccine Drug Substance Development Scientist - VIE Contract

Vaccine Drug Substance Development Scientist - VIE Contract

• Location: Canada, Toronto
• Target start date: 01/08/2026

iMove, the Sanofi VIE Program, is available to citizens of the European Economic Area (EU + Norway, Liechtenstein and Iceland) aged between 18 and 28.

PLEASE NOTE that since this program is primarily an international development program, candidates cannot apply to a VIE assignment in their own country of citizenship.

PLEASE NOTE that applications that are only submitted in French cannot be considered by our non-French speaking partners at Sanofi worldwide. Therefore, only applications that are submitted in English will be considered. Please make sure to apply with your personal email address.

About the job

As Vaccine Drug Substance Development Scientist VIE within our CMC (Chemistry, manufacturing and controls) Development team, you will have the opportunity to develop the ability to lead and function creatively within a team, while maintaining attention to strict compliance. You will acquire knowledge of industry constraints and regulations.

The Vaccine Drug Substance Development (VDSD) within the Global Bioprocess Development (GBD) department actively supports process development of novel vaccine candidates utilizing techniques such as viral cell culture, bacterial fermentation, molecular biology, downstream processing (chromatography, TFF) and supportive analytical techniques. We develop and scale up upstream and downstream processes for new vaccines up to 200L scale.

Join the team protecting half a billion lives every year with next-gen science, mRNA innovation, and AI-driven breakthroughs. In Vaccines, you’ll help advance prevention on a global scale - and shape the future of immunization.

Ready to get started?

About Sanofi

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Main responsibilities:

• Phase I and II drug substance process development for recombinant protein vaccine candidates.
• Plan and execute upstream process optimization and scale-up studies using technologies such as AMBR high-throughput bioreactor system, small and pilot scale bioreactors.
• Plan and execute midstream and downstream process optimization and scale-up studies using technologies such as TECAN high-throughput chromatography screening, AKTAs, Tangential Flow Filtration (TFF) and various filtration methods.
• Supportive analytical testing including viral titration assays, Flow cytometry, protein assays, Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis (SDS-PAGE), Western blot, High-Performance Liquid Chromatography (HPLC), Limulus Amebocyte Lysate (LAL) and others.
• Statistical data analysis, preparation of technical reports and stakeholder presentations.
• Planning, execution and statistical analysis of Design of Experiment studies.
• Tech transfer of processes to Global Clinical manufacturing team or Manufacturing Science and Technology (MSAT).
• Contribute to Sanofi’s digital and automation initiatives.

About you

Experience:

• Knowledge and experience with bioprocessing methods and process scale-up.
• Demonstrated experience with mammalian cell culture and downstream processing.
• Experience in analytical techniques such as titration assays, flow cytometry, protein assays (BCA), SDS-PAGE, Western blot, HPLC would be an asset.

Soft and Technical skills:

• Mandatory Computer skills: Word, Excel, PowerPoint.
• Expertise in Statistical analysis and software (JMP, GraphPad Prism) would be an asset.
• Leadership skills.
• Demonstrate accountability and motivation.
• Strong attention to detail and analytical skills.
• Excellent communication and interpersonal skills.
• Desire to work within a team environment.

Education:

• Master’s degree in Biochemical Engineering / Life Sciences / Biology / Immunology / Biochemistry disciplines.

Languages:

• Fluent English (written and verbal).

Why choose us?

• Be part of a pioneering biopharma company where patient insights shape drug development.
• Work at the forefront of AI-powered science that accelerates discovery and improves outcomes.
• Collaborate beyond your expertise, sparking new ideas with diverse, multidisciplinary teams.
• Share knowledge with leading scientists, engineers, and experts in a purpose-driven community dedicated to protecting millions worldwide.
• Be part of a company that believes in the future with significant investment annually in manufacturing innovation.
• Help create sustainable vaccine solutions, from reducing carbon emissions in production to increasing global access to life-saving immunizations.
• Gain hands-on experience in state-of-the-art digital and AI-powered manufacturing facilities, where you can be part of industry-leading advancements.

iMove is a unique program tailored for European youth interested in challenging themselves with meaningful assignments across the globe. At Sanofi we have a strong ambition to invest in young talents who will drive the success of Sanofi tomorrow.

Sanofi’s Work Abroad Program, iMove, offers jobs-assignments with actual responsibilities and a perspective to grow. We provide those opportunities in various functions such as: marketing, finance, regulatory, supply chain, clinical trials, production, etc. and in more than 40 countries. Sanofi unites people who are passionate about solving healthcare needs across the world. Joining our iMove Work Abroad Program is a unique opportunity to make a difference through your work.

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