Head of Global Data and Computational Science - Vaccines Research and Development

Job title: Head of Global Data and Computational Science - Vaccines Research and Development

Location: Waltham, MA / Swiftwater, PA

About the job

Are you ready to shape the future of medicine? The race is on to harness the power of data and computational science to accelerate vaccine discovery and development. Your skills could be critical in helping our teams make faster, smarter decisions. Join our Vaccines R&D Leadership Team at Marcy l'Etoile as Head of Global Data & Computational Science and you'll define and execute our data strategy, building cutting-edge computational capabilities that transform how we design, develop, and deliver vaccines to patients around the world.

We are an innovative global healthcare company that helps the world stay ahead of infectious diseases by delivering more than 500 million vaccine doses a year. Across different countries, our talented teams are exploring new technologies to protect people and promote healthy communities. We chase the miracles of science every single day, pursuing progress to make a real impact on millions of patients around the world.

In the context of the R&D evolution. our position is currently in Project Status, where the scope of this position may continue to evolve.

Our Team

The Global Data & Computational Science team is at the forefront of Sanofi's digital transformation in vaccine R&D. We are a diverse, international group of data scientists, computational biologists, bioinformaticians, and AI specialists united by a shared passion for leveraging data to accelerate vaccine innovation and improve patient outcomes.

Leadership & Structure:

• You will report directly to the Head of Vaccines R&D (Jean-Francois Toussaint)

• You will be a member of the Vaccines R&D Leadership Team (VRDLT), contributing to strategic decisions and portfolio priorities

• You will lead and develop the Global Data & Computational Science team

What we do:

• Build and deploy cutting-edge data science and AI/ML capabilities to accelerate vaccine discovery and development

• Develop computational models and predictive tools that support go/no-go decisions across the vaccine pipeline

• Integrate and analyze complex biological, clinical, and real-world datasets to generate actionable insights

• Partner with R&D functions to embed data-driven approaches into vaccine research workflows

• Shape Sanofi's data strategy and digital transformation agenda within Vaccines R&D

Who we are:

• A multicultural team based at Marcy l'Etoile, Europe's leading vaccine R&D hub, with global connections

• Data scientists and computational biologists with deep expertise in AI, machine learning, and bioinformatics

• Strategic thinkers who bridge the gap between cutting-edge technology and real-world vaccine development

• Collaborative leaders committed to cross-functional alignment and continuous innovation

Our culture:

• We value scientific rigor combined with entrepreneurial thinking

• We communicate transparently and embrace calculated risk-taking

• We celebrate diversity of thought as a source of innovation

• We are committed to work-life balance and professional development

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Main responsibilities:

• Define and execute a comprehensive data and computational science strategy aligned with Vaccines R&D portfolio priorities and Sanofi's broader digital transformation agenda

• Build and deploy AI/ML, bioinformatics, and computational modeling capabilities that accelerate vaccine discovery, development, and clinical decision-making

• Lead the integration of diverse data sources (genomics, proteomics, clinical, real-world) to generate actionable insights across the vaccine pipeline

• Partner closely with Vaccines R&D functions, Digital, and IT teams to embed data-driven approaches into research and development workflows

• Establish data governance frameworks, quality standards, and best practices to ensure data integrity, security, and compliance across Vaccines R&D

• Drive external collaborations with academic institutions, technology companies, and data consortia to bring state-of-the-art computational capabilities into Sanofi

• Lead and develop a high-performing, multidisciplinary team of data scientists, computational biologists, and bioinformaticians

• Represent Vaccines R&D in internal and external scientific and digital forums, positioning Sanofi as a leader in data-driven vaccine innovation

About you

• PhD or MD/PhD in Computational Biology, Bioinformatics, Data Science, Immunology, or related field; MBA or executive business education is a strong asset

• Extensive experience in data science, computational biology, or bioinformatics within the biopharmaceutical or vaccine industry

• Proven track record of building and deploying AI/ML and computational capabilities that have created measurable value in drug or vaccine development

• Deep expertise in machine learning, statistical modeling, bioinformatics, and analysis of complex biological datasets

• Strong understanding of vaccine science, immunology, and translational medicine to contextualize computational findings

• Senior leadership experience managing multidisciplinary teams in matrixed global organizations

• Proven ability to translate complex data insights into clear, actionable recommendations for senior leadership and cross-functional teams

• Experience establishing data governance frameworks and ensuring compliance with data privacy and security regulations

• Strategic and entrepreneurial leader with deep scientific curiosity, exceptional communication skills, and executive presence

• Experience engaging with external technology partners, academic institutions, and data consortia is highly valued

• French: full professional proficiency required (essential for working at Marcy l'Etoile and engaging with French stakeholders)

• English: professional fluency (C1/C2) essential for international collaboration and global representation

Why choose us?

• Bring the miracles of science to life alongside a supportive, future-focused team

• Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave

• Lead one of the industry's most ambitious external innovation agendas, shaping the future of Sanofi's global vaccine pipeline

• Build and influence a world-class ecosystem of academic, biotech, and global health partnerships at the forefront of pandemic preparedness

• Work from Marcy l'Etoile, Europe's leading R&D hub for vaccine innovation, with true global impact and access to Sanofi's worldwide network

• Benefit from flexible hybrid work arrangements supporting work-life balance while being part of a multicultural, international team

• Access to executive development programs and international mobility opportunities within Sanofi's global R&D organization

Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.