MES Cloud Engineer

About the Job

• Company Context

• Sanofi's strategic direction is to standardize processes across sites, embrace digital transformation of its Manufacturing & Supply perimeter, simplify its current solution landscape, and leverage advanced technologies to bring business value.

• The MARS (MES Accelerated Roadmap @ Sanofi) program aims to implement Computer-assisted batch review, enabled by the definition and roll-out of a core Manufacturing Execution System (MES). This program will transform Sanofi plants, improving compliance, cost, and cycle time performance.

• Over recent years, Sanofi has deployed various Production sites across GBUs (multiple pharmaceutical processes, Weighing & Dispensing & full MES), with a second wave currently in motion. This represents a strategic opportunity for Manufacturing & Supply Transformation to:

• Design standardized end-to-end processes to generate business value and deliver best-in-class solutions to industrial sites, with high focus on electronic batch record management & review by exception process

• Deliver innovative "state of the art" tools enabling performance for manufacturing processes

• Allow new generation of deployment – more Agile & business centric

• Maintain robust and highly available solutions to operate industrial processes efficiently

• Mandate:

• As the MES Cloud Engineer, you provide specialized expertise in cloud-based Manufacturing Execution Systems (MES), focusing on modern IAAS/PaaS deployments and architecture. You lead the implementation and management of cloud-based MES solutions, ensuring proper integration with Sanofi's manufacturing processes and alignment with business objectives.

Main Responsibilities:

• Cloud MES Implementation:

• Oversee and drive the deployment of MES applications from development to production in cloud environments.

• Implement and manage cloud-based MES solutions including Werum PAS-X, Siemens OpCenter Execution Pharma, and Opstrakker platforms.

• Cloud Architecture and Optimization:

• Design and implement cloud-native architectures for MES applications, focusing on scalability, reliability, and performance.

• Optimize cloud resource utilization and costs for MES deployments.

• Installation and System Updates:

• Plan and execute MES system installations, upgrades, and patches in cloud environments.

• Manage system migrations between different versions or platforms of Werum PAS-X, Siemens OpCenter Execution Pharma, and Opstrakker.

• Implement and maintain system automation for routine updates.

• MES Migration and Deployment Orchestration:

• Lead technical aspects of MES cloud migration projects, including legacy system transitions.

• Design and implement data migration strategies ensuring data integrity and business continuity.

• Create and maintain documentation for installation and migration procedures.

• Coordinate with vendors and third-party teams for complex deployments and migrations.

• DevOps and Automation:

• Implement DevOps practices for continuous integration and deployment of MES solutions.

• Develop and maintain automation scripts for application deployment and maintenance.

• Integration and Data Management:

• Ensure seamless integration between cloud-based MES and other manufacturing systems (e.g., SCADA, ERP).

• Implement data management strategies including data migration, backup, and recovery in cloud environments.

• Security and Compliance:

• Ensure cloud deployments adhere to Sanofi's cybersecurity standards and industry regulations (e.g., GxP, Data Privacy).

• Validate installations and updates according to GxP requirements.

• Ensure adherence to data integrity requirements in GxP environments.

• Maintain compliance with regulatory standards.

• Performance Monitoring and Optimization:

• Implement monitoring solutions to ensure optimal performance and reliability.

• Analyze system performance and implement improvements to enhance efficiency and reduce downtime.

• Collaboration and Knowledge Sharing:

• Work closely with manufacturing teams, IT, and other stakeholders to align solutions with business needs.

• Provide guidance and training on cloud best practices to relevant teams.

About You

• Required Skills and Qualifications:

• Experience:

• 8+ years of experience in Digital Manufacturing domain with:

• 5+ years of experience on Manufacturing Execution System (MES) within the pharmaceutical industry, with a strong interest in upskilling on emerging technologies and enhancing MES technical capabilities and Industrialization or

• 5+ years of experience with Cloud technologies and DevOps tools, driving automation, scalability, and system reliability/Industrialization, with a strong interest in upskilling in the functional MES domain

• Technical Skills:

• Bachelor's degree in computer science, Engineering, or related field

• Strong experience with cloud platforms (e.g., AWS, Azure, GCP) and IaaS/PaaS deployments

• Expertise in Manufacturing Execution Systems, specifically Werum PAS-X, Siemens OpCenter Execution Pharma, and Opstrakker (elogbook/ eforms)

• Proficiency in DevOps practices, CI/CD pipelines, and infrastructure-as-code

• Proven experience in MES system installations, upgrades, and migrations

• Proficiency in installation qualification (IQ) and operational qualification (OQ) procedures

• Strong experience and knowledge of containerization technologies (e.g., Docker, Kubernetes)

• Strong experience and knowledge on Openshift

• Knowledge/ experience on GITHub

• Knowledge of connectivity, firewall flows, protocols (TLS certificates, HTTPS, Load Balancing, DNS, Egress IP…)

• Understanding of pharmaceutical manufacturing processes and GxP regulations/ computerized system validation

• Knowledge of system validation processes and documentation

• Soft Skills and Mindset:

• Problem-solving and analytical thinking: Ability to diagnose complex technical issues and develop innovative solutions

• Communication and collaboration: Strong interpersonal skills to work effectively with cross-functional teams, vendors, and stakeholders

• Innovation mindset: Proactive approach to identifying opportunities for improvement and optimization

• Adaptability and continuous learning: Willingness to stay current with emerging cloud technologies and MES innovations

• Attention to detail: Thorough approach with focus on quality in execution and rigor in documentation

• Project management: Ability to manage multiple priorities, timelines, and deliverables effectively

• Customer-focused mindset: Understanding of manufacturing operations and commitment to supporting business objectives

• Quality and compliance orientation: Strong commitment to regulatory standards and quality processes

Pursue progress, discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, or gender identity.

Watch our ALL IN videoand check out our Diversity Equity and Inclusion actions at sanofi.com!