Job title: Drug Substance (DS) Industrialization Lead - All Genders

• Aramon or Sisteron, in the beautiful South of France

About the job

We deliver 4.3 billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams. With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families. Your job, as Drug Substance (DS) Industrialization Lead within our Manufacturing Science and Technology (MSAT) team, at our sites Aramon or Sisteron, in the beautiful South of France, will serves as a voice of Manufacturing and Supply (M&S) organization to CMC throughout new process design, scale-up and transfer to commercial manufacturing.

The MSAT team is set to deliver seamless industrialization of Sanofi’s future pipeline as well as securing industrial performance of Manufacturing & Supply by technical support, further improvements, and innovation. This position plays a pivotal role in ensuring that the newly developed pharmaceutical processes have a built-in robustness to perform efficiently and consistently at a commercial scale while maintaining quality and regulatory compliance.

We are an innovative global healthcare company with a focus on immunology that extends to innovation in diabetes and transplant medicine. Across different countries, our talented teams are determined to deliver a best-in-class customer experience using the best of digital, artificial intelligence and personal know-how. With a focus on immunology that extends to innovation in diabetes and transplant medicines, we pursue progress to make a real impact on millions of patients around the world.

Main responsibilities:

The main tasks will be following the design and the development of new industrial processes, their assessment for scalability and final technical transfer to Manufacturing & Supply. A successful implementation will hinge on in-depth process scale-up knowledge, previous experience and collaboration with cross-functional teams including R&D, Quality Assurance, Regulatory Affairs, and Manufacturing.

• Evaluate and optimize manufacturing processes, ensuring the choice of the right processing platform, batch or continuous, scalability, efficiency, and robustness to meet production demands while adhering to regulatory guidelines
• Advising on the drug substance industrial process design, scale-up and implementation at GMP manufacturing site(s) and providing technical on-site support
• Leading a sending or receiving unit of a technology transfer project from R&D to Manufacturing & Supply or from one facility to another both internally and externally
• Leading technology transfer teams, activities, managing the knowledge transfer and having a technical understanding and ownership of the industrial process, its control strategy, design space concepts and associated equipment functionality
• Create and maintain the comprehensive tech transfer documentation, including protocols, reports, and batch records, to ensure compliance with regulatory requirements
• Identifying opportunities for process improvements and implement best practices to enhance the efficiency and effectiveness of tech transfer processes

About you

• Experience(s): Significant experience with process design and scale-up in the pharmaceutical or fine chemicals industry, Worked in areas that intersect across two or more of the following areas: Technology Transfer, Process Engineering, Process Validation, Project Delivery, Manufacturing and R&D, Good understanding of scientific, technical, quality, regulatory and commercial aspects in the pharmaceutical industry
• Knowledge & Competences & Soft skills: Proficiency in data analysis and statistical tools,Good leadership and interpersonal skills, proven ability as team player and ability to manage cross-functional teams in a complex international environment, Ability to influence and lead a group of technical experts and keep things on track, Ability to influence senior stakeholders, facilitate best practice and effectively communicate decisions and direction, Results oriented and capable to deliver under high pressure
• Education: A Master’s- or Ph.D. degree in Chemical Engineering or in Organic Chemistry
• Language(s) : Fluency in French and English, both written and verbal

You should be willing to relocate to sites of process implementation (both national & international), both for validation campaigns and troubleshooting.

Why choose us?

• Bring the miracles of science to life alongside a supportive, future-focused team
• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave