Associate Director - Protein Structural Characterization

Job Title: Associate Director

Location: Framingham, MA

About the Job

We deliver 4.3 billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams. With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families

Sanofi’s Global MSAT (Manufacturing Sciences, Analytics, and Technology) acts as a crucial link between our R&D and Manufacturing entities, playing an instrumental role in enhancing our current portfolio and delivering future launches of high-quality and innovative drugs and vaccines. Global MSAT is a beacon of innovation and process excellence in Manufacturing, this includes guiding the journey of new products from their launch to commercial success, being at the forefront of Data Sciences and Digitalization.

Join a team of talented and passionate international experts, scientists, and project leaders dedicated to inventing, designing, industrializing, and implementing cutting-edge industrial chemical and biological processes, analytical methods, and process modeling to successfully launch 3 to 5 new products per year.

The Associate Director of the Characterization team will lead a group of approximately 5 scientists, whose main mission is to support the extended characterization testing of late stage and commercial biologics (e.g. antibodies, recombinant proteins, fusion proteins, and enzymes, etc).  The Characterization team is responsible for performing the activities to support the elucidation of structure, reference standard characterization, comparability, host cell protein profiling and quantitation, as well as supporting stability assessments and investigation. This position resides within the Analytical Science and Technology (AST) protein characterization group, which is part of the Global MSAT at Sanofi, Framingham, MA. 

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Main Responsibilities:

• Lead and inspire a team of Analytical Scientists by providing both technical guidance and strategic direction, fostering innovation, scientific excellence, and alignment with organizational goals

• Drive team growth and engagement by actively managing team member’s career development through personalized mentorship, performance feedback, training opportunities, and strategic talent planning

• Provide impactful scientific mentorship to direct reports, guiding the design, execution, and interpretation of complex experiments to ensure the strategic alignment with project goals

• Work with a global group of engineers and scientists and lead a team to provide timely analytical testing support of upstream, downstream processes; MSAT development and pilot-scale projects.  Review data for accuracy and compliance to procedures.

• Support analytical method transfer and analytical method qualification studies including projects for internal and external partners

• Ensure compliance with environmental health and safety requirements. This includes, but is not limited to, employee training, documentation, equipment qualification, and data integrity.

• Provide strategic input and direction regarding the evaluation/implementation of new analytical technologies for the characterization of biologics and relevant impurities with an emphasis on state-of-the-art methods and techniques.

• Work independently on design and performing characterization studies, data management, investigations, technical protocol/report writing, support regulatory filings, responses to agency questions and life-cycle management for analytical activities

• Identify potential problems and proactively suggest technical solutions based upon analytical expertise and knowledge of product/process; solve assay/analytically related process problems

• Presenting at internal/external conferences and the preparation of high-quality publications

About You

• Ph.D. in Analytical Chemistry, Biochemistry, or related discipline with at least 7 years of relevant experience working in the biotechnology/pharmaceutical industry or a Master’s Degree with at least 11 years of relevant experience.

• Broad expertise in the characterization of proteins including biophysical techniques to assess higher order structure and mass spectrometry to support PTM analysis and primary sequence verification.

• Proven track record of successfully leading a team.

• Experience supporting regulatory submissions and responding to agency questions.

• Excellent oral and written communication skills, strong problem-solving, and inter-personal skills, collaborative, and self-motivated.

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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